Functional Genomics

formaldehyde crosslinking

tiling and promoter array designs

array detection of binding site

ChIP-chip and ChIP-seq

statistical analysis of array hybridization signal

BIOL5381 (Spring TR 10:00-11:15PM) - GENOMICS

The course will be an expansive coverage of concepts and advances in molecular genetics and genomics. The course will cover the principles of molecular genetics (gene and genome organization, replication, transcription, splicing, and translation) and current notable developments in the broad field of genomics. The students will obtain the understanding of the following from the course: structure and function of genomes; genetic variation, functional genomic elements, RNAs, proteins, and other biological molecules; and genes and pathways associated with disease-related traits, which provide both genetic markers for association studies and variants for identifying candidate disease genes. An important additional learning outcome involves problem-solving skills, which are assessed by student analysis and presentation of published scientific research papers covering various topics in genome biology.